Dr Katrina Lythgoe

Positions

Tutorial Fellow in Biology

Associated Professor (Dept of Biology)

Group Leader (Big Data Institute, Oxford)

Investigator (Pandemic Sciences Institute, Oxford)

Subject

Biology

Qualifications

BA (Oxford)

MSc (Imperial)

PhD (Edinburgh)

Academic Background

I did my PhD in population genetics at the University of Edinburgh before travelling to University of California, San Diego for a Research Fellowship where I spent two years at the lab bench working on the coevolution of bacteria and viruses (phage) that infect them. Following this I completed an MSc in Science Communication before becoming the Editor of Trends in Ecology & Evolution for seven years. Since then, I have held a series of Research Fellowships based first at Imperial College London, and more recently at the University of Oxford in both the Department of Biology and the Big Data Institute. I work on the epidemiology and evolution of viruses, including HIV, Hepatitis B virus, and Hepatitis C virus. More recently I have also worked on SARS-CoV-2 as the genetic lead of the ONS Covid Infection Survey.

Research Interests

The evolution and epidemiology of viruses

Teaching

Undergraduate: Evolutionary Biology, Epidemiology and Infectious Disease. Graduate: Molecular Evolution of Viruses.

Publications

Ghafari et al. 2023. High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from a large community-based surveillance study. medRxiv 2023.01. 29.23285160

Lythgoe & Hall et al. 2021. SARS-CoV-2 within-host diversity and transmission. Science 372:6539

Lythgoe et al. 2021. Estimating hepatitis B virus cccDNA persistence in chronic infection. Virus Evolution 7:veaa063

Raghwani et al. 2018. Evolution of HIV-1 within untreated individuals and at the population scale in Uganda. PLoS Pathogens 14(7):e1007167

Lythgoe et al. 2017. Short-sighted viruses and a germline hypothesis for chronic viral infections. Trends in Microbiology 25(5):336

Fraser et al. 2014. Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective. Science 343:1243727

Email [email protected]

Links

https://www.bdi.ox.ac.uk/Team/katrina-lythgoe

https://www.biology.ox.ac.uk/people/katrina-lythgoe