Dr John Willan
Supernumery Fellow in Clinical Medicine
Consultant Haematologist – Oxford University Hospitals NHS Foundation Trust and Frimley Health Foundation Trust
Honorary Senior Clinical Lecturer in Haematology – Nuffield Division of Clinical Laboratory Science
BA (Cantab), BM BCh (Oxon), DPhil (Oxon), MRCP, FRCPath
I am the Fellow of Clinical Medicine at Brasenose and so am responsible for coordinating, and delivering the college based teaching to students in their clinical years. As the numbers of clinical students in each year are relatively small, I am able to get to know the students well, and I aim to tailor the teaching that is delivered to the needs of the individual students, giving many of the tutorials myself, but also calling on a large network of clinicians affiliated to the college to ensure specialist teaching can be provided as needed.
I have been involved in clinical medicine teaching for many years, previously working as an external tutor of clinical medicine at Magdalen College (2009-2016).
In my role as a clinical haematologist I am heavily involved in the investigation, diagnosis and treatment of patients with haematological disease, especially malignancies such as leukaemia and lymphoma. These patients may often require very intensive treatment (including combination chemotherapy and bone marrow transplantation), and so managing them requires astute clinical acumen, and keeps me involved with all the different fields of medicine. I also manage patients with other haematological diseases such as sickle cell disease, haemophilia and thrombophilia.
I am mostly involved in teaching clinical medicine, though am happy to deliver pre-clinical tutorials as time allows.
Clinical medicine, including bed side examination in all areas of medicine and surgery, communication skills, radiology, blood test interpretation, ECGs etc
I am helping to direct the response of my local NHS hospital to the urgent changes due to the coronavirus (COVID-19) pandemic, and I have published practical guidelines for the management of patients with blood cancers, and advice for hospitals in adapting care that is provided. I am also working with a big data expert to analyse individual patient records to determine whether changes in climate affect the transmission rates of coronavirus, and therefore whether we may expect a reduction in new cases as the Northern hemisphere enters the summer months.
I have a strong interest in the development of machine-learning algorithms to improve risk assessment of patients. I have developed an algorithm which is able (on retrospective data) to outperform current methods of risk assessment of patients with suspected deep vein thrombosis (DVT), and I am now working with leading international researchers to see if this finding can be replicated in prospective data for patients with suspected DVT or pulmonary embolism (PE).
I am also developing a web-based patient management system which uses individualised pharmacokinetic analysis of patients with severe haemophilia to help improve management of this condition. This project has won a local innovation award to support this, and I hope to continue its development with the aim of introducing it at centres around the country.
Selected Publications include:
Care of Haematology Patients in a COVID-19 Epidemic. Willan J, King A, Hayes S, Collins G and Peniket A. British Journal of Haematology. 2020 March 15. doi: 10.1111/bjh.16620
Challenges for NHS Hospitals during COVID-19 Epidemic. Willan J, King A, Jeffery K and Bienz N. British Medical Journal. 2020 Mar 20;368:m1117. doi: 10.1136/bmj.m111
Machine learning algorithms in DVT risk assessment. Willan J, Katz H and Keeling D. Oral presentation at International Society of Thrombosis and Haemostasis Congress, Melbourne, Australia, July 2019.
The use of artificial neural network analysis can improve risk-stratification of patients presenting with suspected deep vein thrombosis. Willan J, Katz H and Keeling D. British Journal Haematology. 2019 April;185(2):289-296.
Reducing the need for diagnostic imaging in cases of suspected deep vein thrombosis. Willan J and Keeling D. British Journal of Haematology. 2019 Feb;184(4):682-684.
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