People

robertsonPosition

Professor of Chemistry and Tutorial Fellow in Organic Chemistry

Qualifications

MA, DPhil (both from Oxford)

Academic Background

Undergraduate in Chemistry at Oxford (1983-1987)

DPhil in Organic Chemistry supervised by Professor Sir J E Baldwin (1987-1990)

Post doctoral research at Columbia University, New York, supervised by Professor Gilbert Stork (1990-1992)

University Lecturer and Tutorial Fellow in Organic Chemistry, Oxford (1992 to date)

Undergraduate Teaching

I cover all aspects of the Organic Chemistry component of Oxford's four year MChem degree

Research Interests

Natural product synthesis and synthetic methodology

Our group carries out research into the chemical synthesis of certain natural products selected because they present unique problems that we think we can solve in unusual and efficient ways. Our goals are to discover new chemistry and to gain deeper insights into reactivity and mechanism. We choose targets with interesting and potentially useful biological activity in part so that we can provide access to non-natural analogues that may be more selective or less toxic. Much of our research is inspired by considerations of how to assemble natural product structures and we also try to develop initially purely mechanistic hypotheses into synthetically useful processes.

Publications Include

1) X Ren, J A O'Hanlon, M Morris, J Robertson, L L Wong, ACS Catal. 2016, 6, 6833

Imidazolidin-4-ones via a Cytochrome P450-Catalyzed Intramolecular C-H Amination

2) M Liebeke, N Strittmatter, S Fearn, A J Morgan, P Kille, J Fuchser, D Wallis, V Palchykov, J Robertson, E Lahive, D J Spurgeon, D McPhail, Z Takats, J G Bundy, Nat. Commun. 2015, 6:7869

Unique Metabolites Protect Earthworms Against Plant Polyphenols

3) W P Unsworth, N Clark, T O Ronson, K Stevens, A L Thompson, S G Lamont, J Robertson, Chem. Commun. 2014, 50, 11393

Rhodium(II)-Catalysed Tandem Aziridination and Ring-opening: Stereoselective Synthesis of Functionalised Tetrahydrofurans

4) J Robertson and K Stevens, Nat. Prod. Rep. 2014, 31, 1721

Pyrrolizidine Alkaloids

5) W P Unsworth, S G Lamont, J Robertson, Tetrahedron 2014, 70, 7388

Substrate Scope and Stereocontrol in the Rh(II)-Catalysed Oxyamination of Allylic Carbamates

6) K Y Seah, S J Macnaughton, J W P Dallimore, J Robertson, Org. Lett. 2014, 16, 884

Synthesis of Pandamarilactone-1

7) B Wu, G C Feast, A L Thompson, J Robertson, J. Org. Chem. 2012, 77, 10623

Synthesis of Stereoisomers of Artemisia and Chrysanthemum Bis(acetylenic) Enol Ether Spiroacetals

8) K Clarke, K Tchabanenko, R Pawlowsky, E Carter, M T King, K Musa-Veloso, M Ho, A Roberts, J Robertson, T B VanItallie, R L Veech, Regul. Toxicol. Pharmacol. 2012, 63, 401

Kinetics, Safety and Tolerability of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate in Healthy Adult Subjects

9) K Stevens, A J Tyrrell, S Skerratt, J Robertson, Org. Lett. 2011, 13, 5964

Synthesis of NP25302

10) W P Unsworth, K Stevens, S G Lamont, J Robertson, Chem. Commun. 2011, 47, 7659

Stereospecificity in the Au-Catalysed Cyclisation of Monoallylic Diols. Synthesis of (+)-Iso-altholactone

Email address

[email protected]

Links

http://users.ox.ac.uk/%7Ejrobert/Home.html