Professor Samira Lakhal-Littleton
Bsc (Hons), DPhil (Oxon), FESC
Tutorial Fellow
I completed a DPhil in Molecular Medicine at the University of Oxford in 2007, then joined the laboratory of Sir Prof Peter Ratcliffe as a postdoctoral researcher. There, my research defined the interplay between Hypoxia Inducible Factors (HIFs) and iron homeostasis, revealing how cellular iron deficiency can engender pseudo-hypoxic (mal)adaptations.
In 2013, I secured a BHF Intermediate Research Fellowship and became an independent principal investigator. I discovered that many cell types depend on regulated iron export to control their iron levels, and demonstrated that failure to do so leads to pathophysiological consequences in the heart, the pulmonary vasculature, the liver, the kidney, and the systemic vasculature.
In 2021, I secured a Senior Research Fellowship from the Medical Research Council (MRC). This work built on discoveries from the BHF Fellowship, to uncover the clinical consequences of iron deficiency and iron overload, and to change clinical practice on iron supplementation, especially in patients with heart failure.
In 2021, I also joined Brasenose as an Associate Professor and Tutorial Fellow. I became Full Professor of Iron Physiology in 2026.
Over the years, I have secured ~£22 million in research funding, including ~£4 million as principal investigator
Besides research and teaching, I contribute to a range of funding and learned bodies, including:
- BHF Clinical Fellowships Committee
- Medical Research Council Experimental Medicine Panel
- Royal Society Research Grants Committee: Biological Science
- UK Research & Innovation (UKRI) Interdisciplinary Assessment College
- Board of Directors of the International BioIron Society
SELECTED PRIZES AND AWARDS
- Membership of Academia Europeae
- Fellowship of the European Society of Cardiology (FESC)
- Physiological Society’s Bayliss-Starling Prize Lecture
- Pulmonary Vascular Research Institute Sheila Glennis Howarth Prize Lecture
I lead the teaching of Preclinical Medicine at Brasenose. I teach Principles of Physiology, Biochemistry and Medical Genetics to the first years, Applied Physiology and Pharmacology to the second years, and a range of Final Honours school (FHS) options to the third years, including Cardiovascular Sciences, Endocrinology , and Applied Human Physiology. I also deliver a number of Lectures to all three years of Preclinical Medicine at Faculty Level.
I also lead Medicine admissions at Brasenose. Together with my colleagues, we seek the select the best and brightest to join the course. Through my teaching, I am passionate about fostering the next generation of clinician scientists.
Unique biochemical properties underpin the essential functions of iron in oxygen transport and oxidative phosphorylation. Those same properties also underpin its propensity to participate in Fenton-type reactions, producing cell-damaging reactive oxygen species. Thus, tight control of iron levels within tissues is paramount for normal physiological function, particularly in tissues of high oxygen demand/flux.
I am a translational scientist. My research focusses on understanding the impact of too little or too much iron on the cardiovascular system, and on translating that understanding into better management of iron status in chronic disorders. To find out more about my research, visit my laboratory’s webpage
For an up-to-date list of publications, visit https://orcid.org/0000-0001-7797-1567
1. Vera-Aviles, M., Kabir, S. N., Christodoulou, M. D., Mohammad, G., Shanmuganathan, M., Kotronias, R., Cleland, J. G. F., Channon, K. M., Lakhal-Littleton, S., & OxAMI investigators (2026). Complex relationship between iron status and outcomes of STEMI: hypothesis-generating study. Cardiovascular research, cvag223. Advance online publication. https://doi.org/10.1093/cvr/cvag223
2. O’Keeffe, H., AlTheyaib, F., Newman, I., Rengarajan, S., Lakhal-Littleton, S., Baricevic-Jones, I., Chinnadurai, R., & Kalra, P. A. (2026). Functional iron deficiency and outcomes in patients with kidney disease. PloS one, 21(3), e0343724. https://doi.org/10.1371/journal.pone.0343724
3. Mollar, A., García-Conejo, C., Revuelta-López, E., Cardells, I., López, R., Del Canto, I., de la Espriella, R., Lopez-Lereu, M. P., Monmeneu, J. V., Maceira, A., Lakhal-Littleton, S., Almenar, L., Cases, A., Peiró, M., Bayés-Genís, A., & Núñez, J. (2026). Changes in platelet count as a marker of myocardial iron uptake after administration of ferric carboxymaltose in patients with heart failure. Scientific reports, 16(1), 5044. https://doi.org/10.1038/s41598-026-35632-
4. Talbot, N. P., Downs, M., Cane, J., Yen, S., Mohammad, G., Gates, A., Snowball, J., Laskawiec-Szkonter, M., Dobson, M., Lakhal-Littleton, S., Johnson, J. S., Rahman, N. M., Gerry, S., Chapman, S. J., & Flight, W. G. (2025). Intravenous iron for the treatment of iron deficiency in adults with cystic fibrosis: a prospective observational cohort study. The European respiratory journal, 66(5), 2500838. https://doi.org/10.1183/13993003.00838-2025
5. Vilaplana-Lopera, N., Kim, J., Nam, G., Tullis, I. D. C., Paillas, S., Ruan, J. L., Lee, P. J., Jiang, Y., Park, S., Hou, T., Nasir, A., Charlesworth, E., Walker, E., Abu-Halawa, A., Hill, M. A., Choi, C., Lee, I. J., Jeong, Y., Lakhal-Littleton, S., Then, C. K., … Moon, E. J. (2025). Tissue-specific iron levels modulate lipid peroxidation and the FLASH radiotherapy effect. Cell death & disease, 16(1), 668. https://doi.org/10.1038/s41419-025-07988-0
6. Lakhal-Littleton, S., & Peyssonnaux, C. (2025). Hepcidin and Tissue-Specific Iron Regulatory Networks. Advances in experimental medicine and biology, 1480, 89–102. https://doi.org/10.1007/978-3-031-92033-2_7
7. Nunez, J., Mollar, A., Vera-Aviles, M., Kabir, S., Shah, A., Polzella, P., Desborough, M., Cardells, I., Minana, G., Del Canto, I., Ferreira, V., Piechnik, S., Maceira, A., & Lakhal-Littleton, S✉. (2025). Baseline serum ferritin predicts myocardial iron uptake following intravenous iron therapy – a hypothesis-generating study. Eur J Heart Fail. https://doi.org/10.1002/ejhf.3730
8. Piechnik, S. K., Polzella, P., Shah, A., Vera-Aviles, M., Kabir, S. N., Desborough, M., Ferreira, V. M., & Lakhal-Littleton, S✉. (2025). Myocardial iron intake following intravenous iron therapy with ferric carboxymaltose is sustained at 1 year despite recurrence of ID. Br J Haematol, 206(1), 349-352. https://doi.org/10.1111/bjh.19915
9. Lakhal-Littleton, S✉. (2025). Anaemia, neurohormonal activation, and myocardial iron depletion in heart failure: can this vicious circle be broken? Eur Heart J, 46(16), 1524-1527. https://doi.org/10.1093/eurheartj/ehae798
10. Talbot, N.P., Downs, M., Cane, J., Yen, S., Mohammad, M., Gates, A., Snowball, J., Laskawiec-Szkonter, M., Dobson, M., Lakhal-Littleton, S., Johnson, J., Rahman, N., Gerry, S., Chapman, S., Flight, W. (2025). Intravenous iron for the treatment of ID in adults with cystic fibrosis. European Respiratory Journal doi 10.1183/13993003.00838-2025 (in press)
11. Vilaplana-Lopera, N., Kim, J., Nam, G., Tullis, I. D. C., Paillas, S., Ruan, J. L., Lee, P. J., Jiang, Y., Park, S., Hou, T., Nasir, A., Charlesworth, E., Walker, E., Abu-Halawa, A., Hill, M. A., Choi, C., Lee, I. J., Jeong, Y., Lakhal-Littleton, S., . . . Moon, E. J. (2025). Tissue-specific iron levels modulate lipid peroxidation and the FLASH radiotherapy effect. Cell Death Dis, 16(1), 668. https://doi.org/10.1038/s41419-025-07988-0
12. Graham, F. J., Masini, G., Lakhal-Littleton, S., Clark, A. L., Cleland, J. G. F., & Pellicori, P. (2025). ID in Cardiovascular Disease- Diagnosis, Clinical Implications, and Future Directions. Circ J. https://doi.org/10.1253/circj.CJ-25-0220
13. Vera-Aviles, M*., Kabir, S. N*., Shah, A*., Polzella, P., Lim, D. Y., Buckley, P., Ball, C., Swinkels, D., Matlung, H., Blans, C., Holdship, P., Nugent, J., Anderson, E., Desborough, M., Piechnik, S., Ferreira, V., & Lakhal-Littleton, S✉. (2024). Intravenous iron therapy results in rapid and sustained rise in myocardial iron content through a novel pathway. Eur Heart J, 45(42), 4497-4508. https://doi.org/10.1093/eurheartj/ehae359
14. Cleland, J. G. F., Pellicori, P., & Lakhal-Littleton, S. (2024). Low Serum Ferritin Might Predict Incident Heart Failure: But Why and Is It Clinically Useful? JACC Heart Fail, 12(3), 549-551. https://doi.org/10.1016/j.jchf.2023.12.012
15. Lakhal-Littleton, S✉., & Cleland, J. G. F. (2024). ID and supplementation in heart failure. Nat Rev Cardiol, 21(7), 463-486. https://doi.org/10.1038/s41569-024-00988-1
16. Loick, P*., Mohammad, G. H*., Cassimjee, I., Chandrashekar, A., Lapolla, P., Carrington, A., Vera-Aviles, M., Handa, A., Lee, R., & Lakhal-Littleton, S✉. (2023). Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol, 43(5), 713-725. https://doi.org/10.1161/ATVBAHA.123.319224
17. Nair, M., Choudhury, S. S., Rani, A., Solomi, C. t., Kakoty, S. D., Medhi, R., Rao, S., Mahanta, P., Zahir, F., Roy, I., Chhabra, S., Deka, G., Minz, B., Deka, R., Opondo, C., Churchill, D., Lakhal-Littleton, S., Nemeth, E., & Maat, H. R. I. c. (2023). The complex relationship between iron status and anemia in pregnant and postpartum women in India: Analysis of two Indian study cohorts of uncomplicated pregnancies. Am J Hematol, 98(11), 1721-1731. https://doi.org/10.1002/ajh.27059
18. Liu, Y., Baumann, B., Song, Y., Zhang, K., Sterling, J. K., Lakhal-Littleton, S., Kozmik, Z., Su, G., & Dunaief, J. L. (2022). Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration. Exp Eye Res, 218, 108988. https://doi.org/10.1016/j.exer.2022.108988
19. Mohammad, G., Matakidou, A., Robbins, P. A., & Lakhal-Littleton, S✉. (2021). The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload. Kidney Int, 100(3), 559-569. https://doi.org/10.1016/j.kint.2021.04.034
20. Lakhal-Littleton, S✉. (2021). Advances in understanding the crosstalk between mother and fetus on iron utilization. Semin Hematol, 58(3), 153-160. https://doi.org/10.1053/j.seminhematol.2021.06.003
21. Kalisch-Smith, J. I., Ved, N., Szumska, D., Munro, J., Troup, M., Harris, S. E., Rodriguez-Caro, H., Jacquemot, A., Miller, J. J., Stuart, E. M., Wolna, M., Hardman, E., Prin, F., Lana-Elola, E., Aoidi, R., Fisher, E. M. C., Tybulewicz, V. L. J., Mohun, T. J., Lakhal-Littleton, S., Sparrow, D. B. (2021). Maternal ID perturbs embryonic cardiovascular development in mice. Nat Commun, 12(1), 3447. https://doi.org/10.1038/s41467-021-23660-5
22. Schwartz, A. J., Goyert, J. W., Solanki, S., Kerk, S. A., Chen, B., Castillo, C., Hsu, P. P., Do, B. T., Singhal, R., Dame, M. K., Lee, H. J., Spence, J. R., Lakhal-Littleton, S., Vander Heiden, M. G., Lyssiotis, C. A., Xue, X., & Shah, Y. M. (2021). Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells. Nat Metab, 3(7), 969-982. https://doi.org/10.1038/s42255-021-00406-7
23. Chung, Y. J., Swietach, P., Curtis, M. K., Ball, V., Robbins, P. A., & Lakhal-Littleton, S. (2020). Iron-Deficiency Anemia Results in Transcriptional and Metabolic Remodeling in the Heart Toward a Glycolytic Phenotype. Front Cardiovasc Med, 7, 616920. https://doi.org/10.3389/fcvm.2020.616920
24. Cherubin, S., Peoples, T., Gillard, J., Lakhal-Littleton, S., Kurinczuk, J. J., & Nair, M. (2020). Systematic review and meta-analysis of prolactin and ID in peripartum cardiomyopathy. Open Heart, 7(2). https://doi.org/10.1136/openhrt-2020-001430
25. Kammerer, L., Mohammad, G., Wolna, M., Robbins, P. A., & Lakhal-Littleton, S✉. (2020). Fetal liver hepcidin secures iron stores in utero. Blood, 136(13), 1549-1557. https://doi.org/10.1182/blood.2019003907
26. Kandilci, H. B., Richards, M. A., Fournier, M., Simsek, G., Chung, Y. J., Lakhal-Littleton, S., & Swietach, P. (2020). Cardiomyocyte Na(+)/H(+) Exchanger-1 Activity Is Reduced in Hypoxia. Front Cardiovasc Med, 7, 617038. https://doi.org/10.3389/fcvm.2020.617038
27. Bessman, N. J., Mathieu, J. R. R., Renassia, C., Zhou, L., Fung, T. C., Fernandez, K. C., Austin, C., Moeller, J. B., Zumerle, S., Louis, S., Vaulont, S., Ajami, N. J., Sokol, H., Putzel, G. G., Arvedson, T., Sockolow, R. E., Lakhal-Littleton, S., Cloonan, S. M., Arora, M., . . . Sonnenberg, G. F. (2020). Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing. Science, 368(6487), 186-189. https://doi.org/10.1126/science.aau6481
28. Schwartz, A. J., Das, N. K., Ramakrishnan, S. K., Jain, C., Jurkovic, M. T., Wu, J., Nemeth, E., Lakhal-Littleton, S., Colacino, J. A., & Shah, Y. M. (2019). Hepatic hepcidin/intestinal HIF-2alpha axis maintains iron absorption during ID and overload. J Clin Invest, 129(1), 336-348. https://doi.org/10.1172/JCI122359
29. Lakhal-Littleton, S✉. (2019). ID as a Therapeutic Target in Cardiovascular Disease. Pharmaceuticals (Basel), 12(3). https://doi.org/10.3390/ph12030125
30. Lakhal-Littleton, S✉. (2019). Mechanisms of cardiac iron homeostasis and their importance to heart function. Free Radic Biol Med, 133, 234-237. https://doi.org/10.1016/j.freeradbiomed.2018.08.010
31. Lakhal-Littleton, S✉., Crosby, A., Frise, M. C., Mohammad, G., Carr, C. A., Loick, P. A. M., & Robbins, P. A. (2019). Intracellular ID in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice. Proc Natl Acad Sci U S A, 116(26), 13122-13130. https://doi.org/10.1073/pnas.1822010116
32. Chung, Y. J., Luo, A., Park, K. C., Loonat, A. A., Lakhal-Littleton, S., Robbins, P. A., & Swietach, P. (2019). Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity. JCI Insight, 4(7). https://doi.org/10.1172/jci.insight.125618
33. Baumann, B. H., Shu, W., Song, Y., Simpson, E. M., Lakhal-Littleton, S., & Dunaief, J. L. (2019). Ferroportin-mediated iron export from vascular endothelial cells in retina and brain. Exp Eye Res, 187, 107728. https://doi.org/10.1016/j.exer.2019.107728
34. Baumann, B. H., Shu, W., Song, Y., Sterling, J., Kozmik, Z., Lakhal-Littleton, S., & Dunaief, J. L. (2019). Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration. Am J Pathol, 189(9), 1814-1830. https://doi.org/10.1016/j.ajpath.2019.05.022
35. Lakhal-Littleton, S✉., & Robbins, P. A. (2017). The interplay between iron and oxygen homeostasis with a particular focus on the heart. J Appl Physiol (1985), 123(4), 967-973. https://doi.org/10.1152/japplphysiol.00237.2017
36. Lakhal-Littleton, S✉., Wolna, M., Chung, Y. J., Christian, H. C., Heather, L. C., Brescia, M., Ball, V., Diaz, R., Santos, A., Biggs, D., Clarke, K., Davies, B., & Robbins, P. A. (2016). An essential cell-autonomous role for hepcidin in cardiac iron homeostasis. Elife, 5. https://doi.org/10.7554/eLife.19804
37. Armitage, A. E., Lim, P. J., Frost, J. N., Pasricha, S. R., Soilleux, E. J., Evans, E., Morovat, A., Santos, A., Diaz, R., Biggs, D., Davies, B., Gileadi, U., Robbins, P. A., Lakhal-Littleton, S., & Drakesmith, H. (2016). Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia. J Innate Immun, 8(5), 517-528. https://doi.org/10.1159/000447713
38. Lakhal-Littleton, S✉,. (2016). Ferroportin Mediated Control of Iron Metabolism and Disease. Blood; 128 (22): SCI–21. https://doi.org/10.1182/blood.V128.22.SCI-21.SCI-21
39. Lakhal-Littleton, S✉., Wolna, M., Carr, C. A., Miller, J. J., Christian, H. C., Ball, V., Santos, A., Diaz, R., Biggs, D., Stillion, R., Holdship, P., Larner, F., Tyler, D. J., Clarke, K., Davies, B., & Robbins, P. A. (2015). Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function. Proc Natl Acad Sci U S A, 112(10), 3164-3169. https://doi.org/10.1073/pnas.1422373112
40. El Andaloussi, S., Lakhal, S., Mager, I., & Wood, M. J. (2013). Exosomes for targeted siRNA delivery across biological barriers. Adv Drug Deliv Rev, 65(3), 391-397. https://doi.org/10.1016/j.addr.2012.08.008
41. Lakhal, S*., Talbot, N. P*., Smith, T. G., Privat, C., Nickol, A. H., Rivera-Ch, M., Leon-Velarde, F., Dorrington, K. L., Mole, D. R., & Robbins, P. A. (2012). Regulation of hepcidin expression at high altitude. Blood, 119(3), 857-860. https://doi.org/10.1182/blood-2011-03-341776
42. Casals-Pascual, C., Huang, H., Lakhal-Littleton, S., Thezenas, M. L., Kai, O., Newton, C. R., & Roberts, D. J. (2012). Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria. Haematologica, 97(11), 1695-1698. https://doi.org/10.3324/haematol.2012.065854
43. van Dommelen, S. M., Vader, P., Lakhal, S., Kooijmans, S. A., van Solinge, W. W., Wood, M. J., & Schiffelers, R. M. (2012). Microvesicles and exosomes: opportunities for cell-derived membrane vesicles in drug delivery. J Control Release, 161(2), 635-644. https://doi.org/10.1016/j.jconrel.2011.11.021
44. El-Andaloussi, S., Lee, Y., Lakhal-Littleton, S., Li, J., Seow, Y., Gardiner, C., Alvarez-Erviti, L., Sargent, I. L., & Wood, M. J. (2012). Exosome-mediated delivery of siRNA in vitro and in vivo. Nat Protoc, 7(12), 2112-2126. https://doi.org/10.1038/nprot.2012.131
45. Lakhal, S*., Silk, J. D*., Laynes, R., Vallius, L., Karydis, I., Marcea, C., Boyd, C. A., & Cerundolo, V. (2011). IDO induces expression of a novel tryptophan transporter in mouse and human tumor cells. J Immunol, 187(4), 1617-1625. https://doi.org/10.4049/jimmunol.1000815
46. Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. (2011). Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat Biotechnol, 29(4), 341-345. https://doi.org/10.1038/nbt.1807
47. Lakhal, S., & Wood, M. J. (2011). Exosome nanotechnology: an emerging paradigm shift in drug delivery: exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers. Bioessays, 33(10), 737-741. https://doi.org/10.1002/bies.201100076
48. Lakhal, S., & Wood, M. J. (2011). Intranasal exosomes for treatment of neuroinflammation? Prospects and limitations. Mol Ther, 19(10), 1754-1756. https://doi.org/10.1038/mt.2011.198
49. Lakhal, S.✉., Schodel, J., Townsend, A. R., Pugh, C. W., Ratcliffe, P. J., & Mole, D. R. (2011). Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis. J Biol Chem, 286(6), 4090-4097. https://doi.org/10.1074/jbc.M110.173096
50. Lakhal, S.✉., Talbot, N. P., Crosby, A., Stoepker, C., Townsend, A. R., Robbins, P. A., Pugh, C. W., Ratcliffe, P. J., & Mole, D. R. (2009). Regulation of growth differentiation factor 15 expression by intracellular iron. Blood, 113(7), 1555-1563. https://doi.org/10.1182/blood-2008-07-170431 [
51. Lakhal, S.✉ (2006) Investing in Immunosurveillance: Recruiting Immune Effectors for Tumor Therapy. IBScientific 2, 1751-1716.
52. Lakhal, S., Lovat, L., Swallow, D (2004) MUC2 and MUC4 Gene Polymorphism in Oesophageal Cancer. Genetics Society News 50:20.
Preprint & under Review
53. Vera-Aviles, M., Sinaida, C., Kabir, S. N., Christodoulou, M. D., Kasner, S., Frost, A., Heather, L., Aye, C., Arulalagan, A., Samuels, F., Raman, B., Leeson, P., Nair, M., & Lakhal-Littleton, S. (2026). Impact of antenatal iron deficiency on maternal heart function—A hypothesis-generating translational study. https://doi.org/10.64898/2026.03.06.26347784
Book chapters
54. Lakhal-Littleton, S.✉., & Peyssonnaux, C. (2025). Hepcidin and Tissue-Specific Iron Regulatory Networks. Adv Exp Med Biol, 1480, 89-102. https://doi.org/10.1007/978-3-031-92033-2_7
55. Lakhal-Littleton, S. (2025). ID in Cardiology. Iron in Clinical Practice. https://doi.org/10.1002/9781394210916.ch11
56. Lakhal-Littleton, S. (2019). Cardiomyocyte hepcidin: From intracellular iron homeostasis to physiological function. Vitam Horm, 110, 189-200. https://doi.org/10.1016/bs.vh.2019.01.009
Conference abstracts
57. Lakhal-Littleton, S✉., Crosby, A., Frise, M. C., Mohammad, G., Carr, C. A., Loick, P. A. M., & Robbins, P. (2019). A. ID in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension through endothelin-1. Heart 2019;105:A142. https://doi.org/10.1136/heartjnl-2019-BCS.168
58. Schwartz, A. J., Goyert, J. W., Solanki, S., Kerk, S. A., Chen, B., Castillo, C., Hsu, P. P., Do, B. T., Singhal, R., Dame, M. K., Lee, H. J., Spence, J. R., Lakhal-Littleton, S., Vander Heiden, M. G., Lyssiotis, C. A., Xue, X., & Shah, Y. M. (2017). Loss of local hepcidin decreases tumorigenesis in colorectal cancer. American Journal of Hematology. 92(8). E178-E506 https://doi.org/10.1002/ajh.24812
59. Lakhal-Littleton, S✉., Wolna, M., Chung, Y. J., Christian, H. C., Heather, L. C., Brescia, M., Ball, V., Diaz, R., Santos, A., Biggs, D., Clarke, K., Davies, B., & Robbins, P. A. (2017). The cardiac hepcidin/ferroportin axis is essential for cardiac iron homeostasis and function. Heart 2017;103:A137. https://doi.org/10.1136/heartjnl-2017-311726.202
60. Chung, Y.J,. Wolna, M,. Robbins, P,. Lakhal-Littleton, S. (2015). Iron-dependent epigenetic regulation by the histone demethylase kdm4a in the heart. Am. J. Hematol., 91: E20-E266. https://doi.org/10.1002/ajh.24277
61. Lakhal-Littleton, S✉., Biggs, D., Diaz, R., Santos, A., Preece, C., Davies, B., & Robbins, P. (2013). The roles of hepcidin and ferroportin in autocrine regulation of iron levels. American Journal of Hematology, 88(5), E49–E49. https://doi.org/10.1002/ajh.23453